Albumin solution as an important component of intensive infusion therapy in women with preeclampsia

نویسندگان

چکیده

The aim of the study is to determine efficiency and effectiveness albumin solution in intensive infusion therapy for pregnant women with preeclampsia based on measuring indicators central peripheral hemodynamics, body water compartments, markers inflammation. 60 were divided into two groups examined. first group (n=30) included whose average age was 30.06±5.13 years, gestation period – 260.18±6.34 days. 16.7% this had moderate preeclampsia, 83.3% severe preeclampsia. Patients received standard according approved treatment protocols. second women, 30.62±6.02 pregnancy 258.75±5.74 patients therapy, like but combination a continuous 20% (8 ml/h 1 st day; 4 2nd 3rd day) furosemide (0.05 mg/kg/h 1st 0.025 72 hours starting from moment end vaginal delivery or Cesarean section surgery. comparative analysis showed that dynamics changes main homeostasis, compartments inflammation parturient strongly depend type therapy. In administration immediately after ensures normalization till 7th day postpartum period. It result rapid decrease total volume fluid (by 17.2%, p<0.001 baseline) interstitium 31.8%, prenatal level). provided helps ensure eukinetic blood circulation 5th already. also accompanied by restoration adaptation mechanisms participate maintaining proper functioning cardiovascular system. use reduces degree background inflammatory process 3.8 times (according index activity IL-6/IL-10) which comes along

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ژورنال

عنوان ژورنال: ??????? ???????????

سال: 2022

ISSN: ['0373-658X']

DOI: https://doi.org/10.26641/2307-0404.2022.4.271184